MAT Clinics in Minnesota: Methadone, Suboxone & Vivitrol Treatment

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Find My Treatment Options

For an overdose or immediate medical danger, call 911. For crisis support, call or text 988. SAMHSA National Helpline: 1-800-662-4357.

MATClinicGuide.com provides education and treatment-navigation support, not medical care. This number reaches our navigation line rather than the clinics listed here; calls may connect to participating providers or navigation partners. Confirm services directly with the clinic.

MAT Treatment Options in Minnesota by Medication

Medication assisted treatment in Minnesota includes methadone, buprenorphine and naltrexone. The right option depends on medical needs, access to a prescriber and personal preferences; a clinician can help explain the differences.

Methadone clinics in Minnesota

Minnesota has 16 Medicare-enrolled opioid treatment program (OTP) locations across 11 cities, with 12 in the Twin Cities metro. Methadone for opioid use disorder is dispensed through certified OTPs, usually with frequent visits early in care. Someone in Brainerd or Duluth may have a local listed program, while residents of nearby rural counties may face longer travel. Learn about methadone treatment and what an OTP does.

An OTP can assess medication needs, explain dosing and discuss whether take-home doses may become appropriate. Federal standards create room for individualized decisions, but an individual clinic determines a treatment plan.

Suboxone doctors and buprenorphine providers in Minnesota

Suboxone and other buprenorphine medications may be prescribed in appropriate outpatient medical settings rather than only in methadone OTPs. That makes this treatment especially relevant for people in communities such as Bemidji, Mankato and Moorhead that have no OTP in the CMS list. Use Fast-Tracker or FindTreatment.gov to identify a provider and ask about new-patient appointments.

In Minnesota, prescribing may involve in-person care or eligible telehealth visits depending on current rules and the clinician’s assessment. Read the buprenorphine and Suboxone guide and MAT versus MOUD terminology.

Long-acting buprenorphine injections: Sublocade and Brixadi

Some patients and clinicians choose longer-acting injectable buprenorphine rather than daily self-administered medication. In Minnesota, availability depends on which programs have trained clinicians, the specific medication and coverage arrangements. Ask local clinics about injection services, eligibility, follow-up plans and the steps required before the first dose.

This form of care may reduce the burden of daily medication routines for certain patients, though it does not eliminate follow-up. Learn more in the Sublocade medication overview and ask a clinician how it compares with other buprenorphine options.

Vivitrol and naltrexone in Minnesota

Vivitrol is an extended-release naltrexone injection, and it does not contain an opioid. A person generally needs to be opioid-free before starting it to avoid precipitated withdrawal; the treatment team must assess timing and safety. Medical Assistance covers naltrexone treatment for OUD under the federal Medicaid medication coverage requirement.

For Vivitrol Minnesota availability, search local addiction-medicine providers or ask Fast-Tracker about relevant programs. Compare options in the naltrexone and Vivitrol treatment guide; do not stop opioids or start medication without clinical guidance.

Paying for MAT in Minnesota

Minnesota Medical Assistance is the state’s Medicaid program, and Minnesota also offers MinnesotaCare, a Basic Health Program for eligible people with somewhat higher incomes. Minnesota implemented Medicaid expansion on January 1, 2014, according to KFF.

Minnesota Medicaid and Medical Assistance

Federal Medicaid rules require coverage of methadone, buprenorphine and naltrexone for opioid use disorder. Plan rules, prior authorization and where a member can fill a prescription may differ, so the provider and payer should review the specific benefit. Visit the Minnesota DHS health care programs page for enrollment information.

Medicare and OTP care

Medicare Part B includes an opioid treatment program benefit for eligible services provided by enrolled OTPs. The 16 Minnesota clinics above appear in a CMS Medicare enrollment file, but each patient should check coverage, network status and cost sharing. Some take-home prescribed medications are billed through Medicare Part D, depending on the medication and plan.

Private insurance

People with employer coverage or individual health plans should ask whether the insurer has in-network Minnesota OTPs, buprenorphine prescribers or injection providers. Mental health and substance use coverage protections do not guarantee every particular facility, treatment schedule or drug brand is covered.

Without insurance or with limited income

Ask a Minnesota clinic whether it offers a sliding fee scale, financial screening or help connecting to available public benefits. Fast-Tracker may help identify programs with openings, and DHS can provide information on Medical Assistance and MinnesotaCare. Start with insurance coverage information, insurance verification or treatment costs and insurance.

Opioid Overdose in Minnesota: Why Access Matters

Minnesota recorded 995 drug overdose deaths in 2024, compared with a peak of 1,384 in 2022, according to CDC data presented by KFF and USAFacts. The state’s all-drug age-adjusted death rate fell from 24.8 per 100,000 in 2022 to 17.3 in 2024; the national 2024 rate was 23.1.

The Minnesota opioid overdose death rate increased from 7.8 per 100,000 in 2019 to 18.7 in 2022, then decreased to 11.9 in 2024. The national opioid rate was 16.0 in 2024. Declining deaths are encouraging, but the uneven geographic distribution of the 16 Medicare-enrolled OTPs still makes access a practical issue for some residents.

Naloxone can reverse opioid overdose, and Minnesota has free naloxone and training through syringe service programs. Learn how to recognize an overdose and use naloxone.

Minnesota Resources & Helplines

The Minnesota Department of Human Services coordinates behavioral health services, while the Department of Health provides overdose prevention resources. Treatment searches can begin with Fast-Tracker and national support lines.

Naloxone and Steve’s Law

Minnesota allows someone to administer naloxone in good faith during an opioid overdose emergency. Minn. Stat. § 604A.05 also provides defined protections for people who seek overdose assistance, subject to conditions including giving identifying information, remaining at the scene and cooperating. These protections have limits; read the Minnesota statute for details.

MDH provides information about overdose response, training and syringe service programs. Naloxone is also available over the counter; taking steps to have it nearby can be important for people at risk and loved ones.

How to Choose a MAT Clinic in Minnesota

Choosing a Minnesota MAT clinic starts with deciding which medication options you want to discuss and identifying a provider that can assess your needs. Questions about travel, insurance and intake matter, especially away from the Twin Cities.

Questions to ask a methadone OTP

• Do you currently accept new patients, and how is intake scheduled?
• How often must I attend in person during the first weeks?
• How do you evaluate take-home dose eligibility?
• Do you accept Medical Assistance, Medicare or my private insurance?
• Can you coordinate a transfer or guest dosing when travel is necessary?

Questions to ask a buprenorphine provider

• Do you prescribe buprenorphine or Suboxone for opioid use disorder?
• Can the first assessment happen by telehealth under current rules?
• Do you offer or refer for Sublocade, Brixadi or Vivitrol?
• How do medication follow-ups, pharmacy arrangements and costs work?
• Is counseling available if I want it, without delaying medication assessment?

What happens at a first visit

1. Discuss symptoms, history, medication use and personal treatment goals.
2. Review clinical safety, assessment requirements and possible medication options.
3. Discuss visit schedules, payment, follow-up and overdose prevention planning.

Treatment may continue for different lengths of time based on clinical need. Read how long MAT can last and the role of counseling in MAT.

Sources, Methodology & Editorial Standards

1. CMS Medicare Opioid Treatment Program Providers, September 8, 2026
2. Minnesota Department of Health substance use disorder resource sheet
3. Minnesota Department of Health naloxone and training resources
4. Minnesota Statutes § 604A.05, overdose medical assistance protections
5. Minnesota Fast-Tracker treatment resource
6. KFF state Medicaid expansion status, October 2026
7. KFF overdose death rates, CDC NCHS data through 2024
8. USAFacts Minnesota overdose deaths, CDC data through 2024

The clinic directory was compiled from the CMS Medicare Opioid Treatment Program Providers file dated September 8, 2026, and arranged by city with duplicate addresses removed. Coverage, public health and treatment information was summarized from the Minnesota and national sources above. MATClinicGuide.com does not own or operate any listed clinic.

Medical information: This page is educational, not a medical evaluation, diagnosis, prescription or treatment advice. A qualified clinician should evaluate medication suitability, dosing, pregnancy-related care and withdrawal concerns. For emergency symptoms or overdose, call 911; for crisis support, call or text 988.

Referral disclosure: MATClinicGuide.com is an educational and treatment-navigation resource, not a treatment provider. Calls to our advertised number go to our treatment-navigation line rather than to an individual directory clinic. Calls may be answered by or routed to participating treatment providers or navigation partners. Confirm clinic services, availability, insurance and treatment terms directly with the clinic.

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